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Clean Uninstallation of Python Packages after Ubuntu Upgrade

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I recently upgraded a machine from Ubuntu Server 16.04 LTS to 18.04 LTS using command line. As a result, the built-in Python installation is upgraded from Python 3.5 to 3.6. And it seems that all the Python packages previously installed using pip3 are no longer accessible. I plan to clean up all those packages and use conda for Python package management. My question is, what is the best practice for a clean uninstallation of those inaccessible packages in this case?

The old packages installed via pip3 were primarily located under /usr/local/lib/python3.5/ and ~/.local/lib/python3.5/. But there could be other leftover files, e.g., under /usr/local/bin/. I would like to remove all of related files that came with pip3 install.


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